Biophysics and Cancer
Azadeh Hekmat; Setareh Zahedian
Abstract
Introduction and aim: Cold atmospheric plasma (CAP) is a new anti-cancer therapeutic method in the field of plasma medicine, with high selectivity to kill cancer cells more than normal cells. In recent years plasma-activated solutions, specifically plasma-activated medium (PAM) have also shown their ...
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Introduction and aim: Cold atmospheric plasma (CAP) is a new anti-cancer therapeutic method in the field of plasma medicine, with high selectivity to kill cancer cells more than normal cells. In recent years plasma-activated solutions, specifically plasma-activated medium (PAM) have also shown their selective anti-cancer effect, like direct CAP treatment. Different sources produce plasma, and the purpose of this research was to investigate the effect of various plasma production devices on the growth of MCF-7 breast cancer cells.Methods: The effect of PAM produced from three different sources of cold atmospheric plasma on the human breast cancer cell line (MCF-7) was compared using the MTT test. Results: The cells treated with PAM of the Parla plasma jet in 1, 2, 3, and 4 minutes decreased the viability of the cells by 35%, respectively. The cells treated with PAM of electric charge discharge plasma device caused significant cell death, but the culture cells treated with PAM of argon plasma jet device did not affect cell survival.Conclusion: The present findings showed that the type of cold atmospheric plasma source is effective on cell survival rate.
