Cell culture and Tissue culture
The role of PM2.5 pollution on changes in blood and inflammatory indices in rat lung tissue

mahdi farhadi mahalli; pejman mortazavi; Saeed Motesaddi Zarandi; akram eidi

Volume 3, Issue 2 , November 2023, , Pages 1-8


  Introduction and aim: In this study, we have investigated the role of gaseous pollutants and PM2.5 on changes in some blood parameters and inflammatory tissue factors in a rat model in treatment period of six months.Methods: A total of 24 Wistar rats were randomly divided into 3 groups: receiving PM2.5 ...  Read More

Cell culture and Tissue culture
Isolation,, propagation and optimization of SPF egg fibroblast cell culture

Mohamad Mahdi Ramezani; Ali Asghar Razmaraei Iranagh; Reaza Aghaei; Nasser Razmaraii

Volume 3, Issue 2 , November 2023, , Pages 9-18


  Introduction and aim: Cultured poultry cells can provide a valuable resource for various researchers in the field of pharmaceutical studies, the culture of poultry and human viruses, as well as the production of viral vaccines. Avian cell culture requires an optimal basic medium and currently, there ...  Read More

Cell culture and Tissue culture
The protective effects of Aloe vera and Pisum sativum on the stability of human red blood cells membrane treated with Sulfasalazine

Shahin Seyf; Rahim Ahmadi; Sara Najafi

Volume 2, Issue 3 , December 2021, , Pages 1-6


  Background and aim: Studies show that some plant extracts are effective in improving the lifespan of blood cells, although the mechanism of action is not clear in many cases. Accordingly, the present study investigated the effects of Pissum sativum L and Aloe vera extract on cell membrane stability in ...  Read More

Cell culture and Tissue culture
The effect of busulfan on the expression changes of Nrf -2 and Keap-1 genes in testicular tissue of male Wistar rats

sasan Kalantari; Tahereh Naji; Rahim Ahmadi

Volume 2, Issue 3 , December 2021, , Pages 12-17


  Introduction and Aim:  One of the most well-known side effects of anticancer drugs is disruption of spermatogenesis, which in many cases causes infertility. The present study aimed to evaluate the expression change of Nrf-2 and Keap-1 genes due to peritoneal injection of busulfan in male Wistar ...  Read More

Cell culture and Tissue culture
The effects of Hemorrhois ravergieri saliva on the viability of human dermal fibroblasts (HDF) cells

Arefeh Kamali; Abbas Zare MirakAbadi

Volume 2, Issue 2 , October 2021, , Pages 21-27

  Introduction and Aim: Many colubrid snakes produce toxic oral secretions and some species have caused severe reactions in humans. In this research toxicity of Duvernoy´s gland secretion (DGS) from Hemorrhois ravergieri (aglyph) has been studied.Methods: In this study, the effect of Hemorrhois ravergieri ...  Read More

Cell culture and Tissue culture
Synthesis of sodium alginate nanoparticles containing Agkistrodon halys snake venom and evaluation of biological activity and survival of colon cancer cells (SW-480)

Sahar Salmanzadeh Zehkesh; Naser Mohammadpour Donighi

Volume 2, Issue 2 , October 2021, , Pages 35-42

  Introduction and Aim: Alginate nanoparticles have been used in novel drug delivery systems due to marvelous features including biocompatibility, biodegradable, mucoadhesive, and non-toxic. At present various types of adjuvants are used against snake venom, as a solution, suspension, or emulsion systems, ...  Read More

Cell culture and Tissue culture
Isolation and evaluation of human adipose tissue characterization for preparation of vascular stem cells

Sona Zare; MohammadAli Nilforoushzade; Rahim Ahmadi; Zahra Esmaeili

Volume 2, Issue 1 , August 2021, , Pages 8-14

  Introduction and Aim: Several studies have been carried out on the biological characteristics of a human adipose tissue-derived-stromal vascular fraction. However, investigating this fraction concerning its clinical application is still of significant importance. The aim of this study was to isolate ...  Read More

The toxicity induction in human dermal fibroblasts (HDF) cells by saliva of Echis carinatus sochureki

Abbas Zare MirakAbadi; Parvin Horrieh

Volume 1, Issue 1 , September 2020, , Pages 1-8

  Introduction and Aim: Echis carinatus are small in size and are considered to be very biting invasive snakes. Snake venom is a type of snake saliva that is secreted through the salivary glands and stored in the venom sac. A problem in human societies, especially in rural areas, is snake bites, which ...  Read More