Cell culture and Tissue culture
The protective effects of Aloe vera and Pisum sativum on the stability of human red blood cells membrane treated with Sulfasalazine

Shahin Seyf; Rahim Ahmadi; Sara Najafi

Volume 2, Issue 3 , December 2021, , Pages 1-6

https://doi.org/10.30495/rkctc.2021.19056

Abstract
  Background and aim: Studies show that some plant extracts are effective in improving the lifespan of blood cells, although the mechanism of action is not clear in many cases. Accordingly, the present study investigated the effects of Pissum sativum L and Aloe vera extract on cell membrane stability in ...  Read More

Cell culture and Tissue culture
The effect of busulfan on the expression changes of Nrf -2 and Keap-1 genes in testicular tissue of male Wistar rats

sasan Kalantari; Tahereh Naji; Rahim Ahmadi

Volume 2, Issue 3 , December 2021, , Pages 12-17

https://doi.org/10.30495/rkctc.2022.65731.1035

Abstract
  Introduction and Aim:  One of the most well-known side effects of anticancer drugs is disruption of spermatogenesis, which in many cases causes infertility. The present study aimed to evaluate the expression change of Nrf-2 and Keap-1 genes due to peritoneal injection of busulfan in male Wistar ...  Read More

Cell culture and Tissue culture
The effects of Hemorrhois ravergieri saliva on the viability of human dermal fibroblasts (HDF) cells

Arefeh Kamali; Abbas Zare MirakAbadi

Volume 2, Issue 2 , October 2021, , Pages 21-27

Abstract
  Introduction and Aim: Many colubrid snakes produce toxic oral secretions and some species have caused severe reactions in humans. In this research toxicity of Duvernoy´s gland secretion (DGS) from Hemorrhois ravergieri (aglyph) has been studied.Methods: In this study, the effect of Hemorrhois ravergieri ...  Read More

Cell culture and Tissue culture
Synthesis of sodium alginate nanoparticles containing Agkistrodon halys snake venom and evaluation of biological activity and survival of colon cancer cells (SW-480)

Sahar Salmanzadeh Zehkesh; Naser Mohammadpour Donighi

Volume 2, Issue 2 , October 2021, , Pages 35-42

Abstract
  Introduction and Aim: Alginate nanoparticles have been used in novel drug delivery systems due to marvelous features including biocompatibility, biodegradable, mucoadhesive, and non-toxic. At present various types of adjuvants are used against snake venom, as a solution, suspension, or emulsion systems, ...  Read More

Cell culture and Tissue culture
Isolation and evaluation of human adipose tissue characterization for preparation of vascular stem cells

Sona Zare; MohammadAli Nilforoushzade; Rahim Ahmadi; Zahra Esmaeili

Volume 2, Issue 1 , August 2021, , Pages 8-14

Abstract
  Introduction and Aim: Several studies have been carried out on the biological characteristics of a human adipose tissue-derived-stromal vascular fraction. However, investigating this fraction concerning its clinical application is still of significant importance. The aim of this study was to isolate ...  Read More

Toxicology
The toxicity induction in human dermal fibroblasts (HDF) cells by saliva of Echis carinatus sochureki

Abbas Zare MirakAbadi; Parvin Horrieh

Volume 1, Issue 1 , September 2020, , Pages 1-8

Abstract
  Introduction and Aim: Echis carinatus are small in size and are considered to be very biting invasive snakes. Snake venom is a type of snake saliva that is secreted through the salivary glands and stored in the venom sac. A problem in human societies, especially in rural areas, is snake bites, which ...  Read More