نوع مقاله : مقاله پژوهشی

نویسندگان

1 مرکز درمان ناباروری (IVF) بیمارستان خاتم الانبیا، تهران، ایران

2 گروه زیست شناسی، دانشکده علوم پایه، واحد علوم و تحقیقات تهران، دانشگاه آزاد اسلامی، تهران، ایران،

10.30495/rkctc.2022.68581.1046

چکیده

پیشینه و هدف: آلودگی صوتی از جمله عوامل خطرزا در محیط زیست است. یکی از منابع مهم این آلودگی، صدای ناشی از حمل و نقل شهری به ویژه سیستم راه آهن شهری (مترو) و مراکز تجاری است. در این مطالعه تأثیر آلودگی صوتی بر تغییرات هیستوپاتولوژی کبد و کلیه رت‌های نر نژاد ویستار بررسی شد.
روش و بررسی: ر‌ت‌های نر به طور تصادفی به سه گروه تقسیم‌بندی شدند. رت‌های شاهد در شرایط استاندارد آزمایشگاه و دو گروه تجربی در محدوده بازار بزرگ تهران و حوالی ایستگاه مترو صادقیه (خیابان رز غربی) نگهداری شدند. پس از اتمام هشت هفته مواجهه، تمامی حیوانات به وسیله جابه‌جایی مهره گردن کشته شدند و اسلایدهای بافت کبد و کلیه هر سه گروه مورد تجزیه و تحلیل قرار گرفت.
نتایج: در نمونه‌های کلیه رت‌های قرار گرفته در حوالی مترو صادقیه تهران و بازار بزرگ تهران اختلاف معنی‌داری در میزان حجم کلیه‌ها در بین گروه‌های کنترل و آزمایش وجود نداشت. اما تغییرات بافتی در کبد رت‌های قرار گرفته در حوالی مترو صادقیه دیده شد.
نتیجه‌گیری: نتایج این مطالعه نشان داد که آلودگی صوتی در دو منطقه بازار بزرگ تهران و مترو صادقیه موجب تغییر در بافت کبد می‌شود. لذا اقدامات کنترلی و اصلاحی برای کاهش صدا در این مناطق ضروری به نظر می‌رسد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Evaluation of the effects of noise pollution of Tehran’s grand bazaar and Sadeghiyeh subway on the histopathological changes of liver and kidney of Wistar male rats

نویسندگان [English]

  • Talie Esmaeeli 1
  • Ramazan Khanbabaee 1
  • Azadeh Hekmat 2

1 IVF Research Center, Khatam Alanbia Hospital, Tehran, Iran

2 Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran

چکیده [English]

Background and Aim: Noise pollution is one of the hazardous factors in the environment. One of the major sources of this sort of pollution is the noise produced by urban transportation, mostly subway and business centers. In this study, the noise pollution effects on the histopathological changes in the liver and kidney of Wistar male rats were investigated.
Materials and Methods: Rats were arranged in 3 groups (control, and experimental, n=6). The control group was kept in the standard situation and the experimental groups were kept in Tehran grand bazaar and around sadeghiyeh metro station (west rose street). After eight weeks all animals were euthanized via cervical dislocation and tissue samples stained with hematoxylin and eosin for histopathology evaluation.
Results: In the samples of all the rats located around Sadeghiyeh subway and Tehran's grand bazaar, there is no difference in kidney volume between the control and experimental groups. Nonetheless the destruction of hepatocytes and cell degeneration around the central vein in liver tissue were observed in group placed around Sadeghiyeh subway.
Conclusion: The results of this study showed that noise pollution in the two areas of Tehran's grand bazaar and Sadeghiyeh subway causes changes in liver tissue. Consequently, control and correction measures to reduce noise in these areas seem necessary.

کلیدواژه‌ها [English]

  • Noise pollution
  • Liver tissue
  • Kidney tissue
  • Dosimeters
  • Sadeghiyeh subway
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