Document Type : Original Article


1 IVF Research Center, Khatam Alanbia Hospital, Tehran, Iran

2 Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran



Background and Aim: Noise pollution is one of the hazardous factors in the environment. One of the major sources of this sort of pollution is the noise produced by urban transportation, mostly subway and business centers. In this study, the noise pollution effects on the histopathological changes in the liver and kidney of Wistar male rats were investigated.
Materials and Methods: Rats were arranged in 3 groups (control, and experimental, n=6). The control group was kept in the standard situation and the experimental groups were kept in Tehran grand bazaar and around sadeghiyeh metro station (west rose street). After eight weeks all animals were euthanized via cervical dislocation and tissue samples stained with hematoxylin and eosin for histopathology evaluation.
Results: In the samples of all the rats located around Sadeghiyeh subway and Tehran's grand bazaar, there is no difference in kidney volume between the control and experimental groups. Nonetheless the destruction of hepatocytes and cell degeneration around the central vein in liver tissue were observed in group placed around Sadeghiyeh subway.
Conclusion: The results of this study showed that noise pollution in the two areas of Tehran's grand bazaar and Sadeghiyeh subway causes changes in liver tissue. Consequently, control and correction measures to reduce noise in these areas seem necessary.


Main Subjects

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