نوع مقاله : مروری

نویسندگان

1 گروه بیوشیمی، واحد فلاورجان، دانشگاه آزاد اسلامی، اصفهان، ایران

2 دانشگاه علم و فرهنگ،تهران، ایران

3 موسسه آموزش عالی جهاد دانشگاهی استان اصفهان. اصفهان. ایران

چکیده

پانکراس(لوزالمعده) غده‌ای است در عمق شکم که بین معده و مهره‌های ستون فقرات واقع شده است. مهمترین هورمون ترشح شده از این غده، انسولین می‌باشد. انسولین وارد جریان خون می شود و به بدن کمک می‌نماید تا از انرژی موجود در غذا استفاده کند. حال اگر پانکراس در عملکرد خود دچار اختلال شود، این امر موجب کاهش تولید انسولین در بدن می‌شود که نتیجه آن بروز بیماری دیابت است. برطبق تحقیقات بعمل آمده، گیاهان دارویی بر سلامت پانکراس نقش اساسی داشته و منجر به ترمیم سلول‌های بتا می‌گردد. بر این اساس، در این پژوهش برآنیم تا با بهره‌گیری از روش توصیفی- تحلیلی و با استناد به منابع موجود، ارتباط علّی بین اثرات گیاهان دارویی بر حفاظت و ترمیم سلول‌های بتا پانکراس را مورد بررسی قرار دهیم.
مطالعه گیاهان دارویی نظیر گیاه مریم‌گلی، خرفه، گزنه، گلدر، بامیه، کاکوتی و برگ گردو که در این مقاله کوتاه مورد بررسی قرار گرفتند، نوید دهنده این مطلب است که استفاده از آن‌ها به دلیل دارا بودن ترکیباتی مانند فلاونوئیدها و آنتی‌اکسیدان‌ها می‌تواند موجبات بازسازی و ترمیم سلول‌های بتا جزایر لانگرهانس را از طریق ایجاد ساز و کارهایی فراهم آورد.

کلیدواژه‌ها

عنوان مقاله [English]

Investigating the protective & restorative effects of medicinal plants On pancreatic beta cells

نویسندگان [English]

  • sepideh sadat moghadam ara 1
  • mohadeseh pahlevani 2
  • Masoumeh Sadat Hpr 3
  • Soheil Fatahian 1

1 Department of Biochemistry, Falavarjan Branch, Islamic Azad University, Isfahan, Iran

2 University of Science and Culture, Tehran, Iran

3 ACECR Institute of Higher Education (Isfahan Branch), Isfahan, Iran

چکیده [English]

Pancreas is a gland deep in the abdomen that is located between the stomach and the vertebrae of the spine. The most important hormone secreted from this gland is insulin. Insulin enters the bloodstream and helps the body to use the energy in food. Now, if the pancreas is disturbed in its function, this will reduce the production of insulin in the body, which results in the occurrence of diabetes. According to the research, medicinal plants play an essential role in the health of the pancreas, and preventing the destruction of pancreatic beta cells is an important factor in dealing with diabetes. In this research, we intend to investigate the causal relationship between the effects of medicinal plants on the protection and repair of pancreatic beta cells by using the descriptive-analytical method and referring to the available sources.The study of medicinal plants such as Salvia Officinalis, Purslane, Urtica, Otostegia Persica, Abelmoscus Esculentus, Ziziphora Clinopodioides Lam and Juglans Regia, which were examined in this article, promises that their use is due to the presence of compounds such as flavonoids and antioxidants. It can cause regeneration and repair of the beta cells of the islets of Langerhans through the creation of mechanisms.

کلیدواژه‌ها [English]

  • medicinal plants
  • pancreas
  • islets of Langerhans
  • beta cells
  • diabetes
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